Fluoxymesterone is a synthetic androgenic-anabolic steroid (AAS) that is used primarily in the treatment of hypogonadism (low testosterone levels) and delayed puberty in males. It is also sometimes used off-label to treat breast cancer in women.

As with all AAS, fluoxymesterone carries a number of potential side effects, including liver damage, cardiovascular disease, mood swings, and acne. Its use is generally only recommended under the supervision of a medical professional.

How Does Fluoxymesterone Work?

Fluoxymesterone works by binding to and activating the androgen receptor in cells, leading to an increase in protein synthesis and the development of male sexual characteristics. It also has a strong anti-estrogenic effect, which can make it useful in the treatment of certain types of breast cancer that are estrogen receptor-positive. In addition to its anabolic effects, fluoxymesterone also has androgenic effects, meaning that it can promote the development of male secondary sexual characteristics such as facial hair, deepening of the voice, and an increase in muscle mass. This is why it is classified as an androgenic-anabolic steroid. The exact mechanisms of fluoxymesterone’s actions are complex and not fully understood, but they involve interactions with various cellular signaling pathways and gene expression.

Dosage and Administration of Fluoxymesterone

Fluoxymesterone is available in tablet form and is usually taken orally. The dosage and administration of fluoxymesterone depend on the individual patient’s needs and medical condition.

In general, the recommended starting dose for treating hypogonadism in males is 5 to 20 mg per day, taken in divided doses.

The dose may be increased as needed, up to a maximum of 40 mg per day. For delayed puberty in males, the typical starting dose is 2.5 to 20 mg per day, also taken in divided doses.

For breast cancer in women, the recommended dose is 10 to 40 mg per day. The duration of treatment with fluoxymesterone will depend on the condition being treated and the individual patient’s response to the medication.

It is important to follow the dosage and administration instructions provided by the prescribing healthcare provider and not to exceed the recommended dose or duration of treatment. Fluoxymesterone should be taken with food to reduce the risk of stomach upset.

Side Effects of Fluoxymesterone

Like all androgenic-anabolic steroids, fluoxymesterone can have a number of potential side effects, some of which may be serious. The most common side effects of fluoxymesterone include:

• Acne
• Oily skin
• Increased body hair growth
• Voice deepening or hoarseness
• Enlargement of the clitoris in females
• Mood changes, including aggression, irritability, and depression
• Headaches
• Nausea and vomiting
• Liver damage

More serious side effects of fluoxymesterone can include:

• Cardiovascular problems, including high blood pressure, heart attack, and stroke
• Blood clots
• Abnormal liver function tests or liver damage
• Tumors of the liver
• Abnormal prostate exam or prostate cancer
• Infertility or reduced fertility
• Priapism (persistent and painful erections)
• Changes in cholesterol levels
• Edema (fluid retention)

It is important to seek medical attention if any of these side effects occur while taking fluoxymesterone or any other steroid.

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